Hepatic overexpression of Abcb11 in mice promotes the conservation of bile acids within the enterohepatic circulation
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چکیده
منابع مشابه
Hepatic overexpression of Abcb11 in mice promotes the conservation of bile acids within the enterohepatic circulation.
The bile salt export pump, encoded by ABCB11, is the predominant canalicular transport protein for biliary bile acid secretion. The level of ABCB11 expression in humans is widely variable yet the impact of this variability on human disease is not well defined. We aim to determine the effect of hepatic Abcb11 overexpression on the enterohepatic circulation (EHC) in mice. We used a stable isotope...
متن کاملHepatic overexpression of Abcb 11 in mice promotes the conservation of bile acids within the 1 enterohepatic circulation
29 INTRODUCTION: The Bile Salt Export Pump, encoded by ABCB11, is the predominant canalicular 30 transport protein for biliary bile acid secretion. The level of ABCB11 expression in humans is widely 31 variable yet the impact of this variability on human disease is not well-defined. We aim to determine 32 the effect of hepatic Abcb11 overexpression on the enterohepatic circulation (EHC) in mice...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology
سال: 2013
ISSN: 0193-1857,1522-1547
DOI: 10.1152/ajpgi.00322.2012